Rutgers SHP - RG admin
 
 
 
 
Department of Clinical Laboratory Sciences/Medical Laboratory Sciences
Clinical Laboratory Science
CLSC5123 - Advanced Hematology
 
Course Description
This course provides an in-depth study of the physiology and regulation of the hematopoietic system, and the genetic, molecular and cellular mechanisms underlying the pathophysiology of selected anemias, leukemias and lymphomas. Utilization of appropriate laboratory tests for screening, diagnosis, monitoring and determining prognosis will be discussed and applied through clinical scenarios and case studies. Review of current scientific literature and advanced laboratory practice issues will also be covered. Prerequisites include BS degree with previous course work in Hematology and/or work experience in a hematology clinical laboratory. Web Based.
 
Credits/Modes of Instruction
Credits:  3
Participants should anticipate spending approximately 135 hours on the course, or an average of 9 hours per week for 15 weeks. The course is web-based. Modes of instruction and course format include online instruction, online discussion and assignments, textbook, journal and internet readings, case studies, and directed study.
 
Prerequisites
Bachelor’s degree with previous course work in Hematology and/or work experience in a hematology clinical laboratory; coursework in molecular biology or molecular diagnostics is recommended.
 
Course Goals and Outcomes:
Goals
After completion of the course, the student will have a thorough understanding of 1) the anatomy, physiology and regulation of the hematopoietic system; 2) the genetic, molecular, and cellular mechanisms underlying the pathophysiology of selected anemias, leukemias and lymphomas, 3) the correlation of clinical and laboratory data in these conditions, and 4) the appropriate utilization of laboratory tests for screening, diagnosis, monitoring therapy and prognosis.
 
Outcomes
Upon completion of the course, the student will be able to:
Describe the anatomy of hematopoietic tissue, and the physiology and regulation of hematopoiesis.
Discuss the characteristics of stem cells and their therapeutic uses.
Discuss the etiology and the genetic, molecular and cellular mechanisms underlying the pathophysiology of selected anemias, leukemias and lymphomas.
Describe and interpret clinical laboratory tests used in hematopathology.
Correlate laboratory data with patient history, symptoms and clinical assessment data.
Recommend appropriate laboratory testing based on recognition of abnormal peripheral blood morphologic findings or abnormal laboratory screening results.
Compare and contrast the sensitivity and specificity of laboratory tests in the detection or monitoring of selected hematological abnormalities.
Given a patient case scenario with laboratory data, evaluate the laboratory data to determine the possible diseases, the appropriateness of tests ordered, and the appropriate additional laboratory testing to confirm a diagnosis.
Discuss the laboratory tests needed to monitor therapy to determine efficacy and optimize patient safety.
Interpret and analyze data from the scientific literature.