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Department of Clinical Laboratory Sciences/Medical Laboratory Sciences
Clinical Laboratory Science
CLSC6112 - Advanced Topics in Molecular Diagnostics
Course Description
This course is designed to provide in-depth updates in selected topics in molecular diagnostics to enhance the scientific and technical knowledge of clinical laboratory professionals. Topics to be discussed include but are not limited to: advanced methods in sequencing and automation, pharmacogenomics and personalized medicine, proteonomics, consumer directed testing, and case studies in molecular oncology, hematopathilogy, genetics, and infectious diseases. Review of current scientific literature and advanced laboratory practice issues will also be covered.
Credits/Modes of Instruction
Credits:  3
Participants should anticipate spending approximately 135 hours on the course, or an average of 9-12 hours per week. The course is web-based. Modes of instruction and course format include online instruction, online discussion, journal and Internet readings, written assignments, and directed study.
Baccalaureate degree, completion of CLSC 5112 Molecular Diagnostics.
Course Goals and Outcomes:
The general goal of this course is to prepare laboratory professionals to be knowledgeable of emerging technologies and new diagnostic, prognostic, and monitoring strategies in molecular diagnostics, and to search and interpret the scientific literature in the field.
Upon completion of the course, the student will be able to:
Describe the principles and applications of advanced molecular diagnostic techniques discussed in the course.
Explain mechanisms and regulation of gene expression and technologies used to assess it.
Discuss molecular technologies and applications for the study of epigenetics, proteonomics, pharmacogenetics, and personalized medicine.
Discuss the applications, benefits, and pitfalls of direct-to-consumer genetics testing.
Discuss the principles, applications, advantages, and limitations of molecular tests used for identity testing.
Discuss the principles, applications, advantages, and limitations of molecular tests for screening, diagnosis, monitoring, and determining prognosis in selected disease states in genetics, oncology and hematopathology.
Discuss emerging technologies for molecular diagnostic testing for detection, diagnosis, and monitoring of infectious diseases.
Given a patient case scenario, interpret molecular diagnostic testing for screening, diagnosis, prognosis, risk assessment, and monitoring of selected disease states.
Interpret and analyze data from the scientific literature.